Scientific evidence indicates that ozone depletion over the South Pole is more serious than was suspected a few years ago. As a result, production of the principal ozone-depleting compounds is scheduled to be phased out over the next decade. The impact of the elimination of these chemicals on industries will be immediate and significant, with the aerospace and electronics industries among the most severely affected. Alternative solvents, refrigerants, and foam-blowing agents are being developed, but will not be available in commercial quantities until 1992 at the earliest. Meanwhile, CFC users are working with the chemical manufacturers, EPA, DoD, and various research organizations, to speed up the process of identifying and implementing alternative compounds or processes. Most of the proposed alternatives have some drawbacks when compared with CFCs, but can be implemented safely if the user takes the time to understand the issues thoroughly and involves all affected parties in the decision-making process.